About the role
AI summarisedPortfolio Manager role at Singapore’s national RNA therapeutics initiative, responsible for end-to-end oversight of a diverse biotech asset portfolio from discovery through clinical and commercial stages. Combines scientific depth with commercial acumen to drive strategic decisions, due diligence, IP strategy, stakeholder engagement, and grant management.
ResearchOnsite
Key Responsibilities
- Lead end to end portfolio management across multiple biotech and therapeutic programs, ensuring strategic alignment, prioritisation, and value creation
- Evaluate scientific, technical, and commercial merit of assets across stages of development, supporting go/no go decisions and portfolio optimisation
- Work closely with scientific, clinical, and operational teams to drive progress against defined milestones in fast moving, uncertain environments
- Conduct and/or oversee commercial due diligence for new investment opportunities, technologies, and programs, including market sizing, competitive landscape, value proposition, and risk assessment
- Support investment, partnering, or spin out decisions by integrating scientific, IP, regulatory, and commercial insights into clear recommendations
- Engage with external advisors, KOLs, and industry partners to validate assumptions and strengthen decision making
- Develop and execute IP strategies in collaboration with legal counsel and technology transfer teams to protect and maximise asset value
- Assess freedom to operate, patent landscapes, and IP risks as part of portfolio and diligence activities
- Ensure IP considerations are tightly integrated with scientific and commercial strategies from early stages
- Act as a key interface between internal teams and external stakeholders, including academics, clinicians, industry partners, investors, and government agencies
- Prepare and present high quality materials for senior leadership, boards, and external committees
- Build trusted relationships across a complex ecosystem to accelerate translation and partnerships
Requirements
- PhD in a relevant life sciences discipline (e.g. biomedical sciences, pharmacology, molecular biology, bioengineering, or related field)
- Significant experience across venture capital, consulting, biotech, pharma, or drug development, with exposure to asset centric decision making
- Proven track record in commercial due diligence, portfolio analysis, and strategic evaluation of life science assets
- Hands on experience with intellectual property strategy in a biotech or translational context
- Demonstrated capability in stakeholder management across academia, industry, investors, and public sector funders
- Experience managing or supporting grant funded programs and complex funding structures
- prior experience in ophthalmology or eye-related indications (drug, device, or platform-based)
- exposure to company formation, spin outs, licensing, or strategic partnerships
- Highly agile, adaptable, and comfortable operating in ambiguity
- Strong strategic thinker with the ability to move seamlessly between high level vision and detailed execution
- Credible communicator able to translate complex science into clear commercial and strategic narratives
- Collaborative, proactive, and outcome oriented, with a strong sense of ownership