A*STAR

Clinical Lead, Partnership

A*STAR
ResearchSingaporeOnsitePosted 3 days ago

About the role

AI summarised

The Clinical Lead drives clinical strategy and diagnostic product innovation through multi-stakeholder partnerships. This role bridges clinical expertise and technical development to ensure diagnostic solutions align with global regulatory standards and unmet medical needs.

ResearchOnsiteDiagnostics Development Hub

Key Responsibilities

  • Lead the clinical input and strategy across partnered diagnostic development programs, from early concept to validation and implementation.
  • Lead scoping and identification of companion diagnostics partnership opportunities, as well as partnership engagement with biotech and pharma companies.
  • Engage with clinical, academic, and industry partners to identify unmet clinical needs and translate these into Target Product Profiles (TPPs) and clinical performance specifications.
  • Review, interpret, and integrate relevant clinical guidelines to define use cases and clinical utility frameworks.
  • Advise on clinical study design, endpoints, and patient selection criteria to support product development and regulatory submissions.
  • Coach and mentor internal teams—including partnership, tech teams, QA/RA —to ensure alignment between clinical strategy, product requirements, and partnership goals.
  • Contribute to regulatory and ethics submissions related to diagnostic validation and clinical performance studies.
  • Represent the organization in external meetings, working groups, and consortium activities that advance diagnostic development and clinical adoption pathways.

Requirements

  • PhD in Clinical Sciences, Medicine, or related biomedical field or a Medical Degree (MD/MBBS) from a recognized university.
  • Minimum 10 years’ experience in a clinical leadership role within a diagnostics or pharmaceutical development environment.
  • Demonstrated ability to translate clinical insights into actionable product development specifications.
  • Experience in design and development of companion diagnostics.
  • Deep understanding and experience in diagnostic development lifecycles, including analytical and clinical performance evaluation, clinical validation studies, and evidence generation.
  • Practical knowledge of international clinical and regulatory frameworks governing diagnostic products (e.g., HSA, FDA, IVDR, NMPA).
  • Excellent communication and stakeholder management skills with experience engaging clinicians, researchers, regulators, and industry partners.
  • Experience leading clinical programs in genomics, molecular diagnostics, or infectious disease testing.
  • Familiar with health economics, clinical utility studies, or clinical implementation pathways.
  • Proven record of contributing to cross-sector partnerships or consortium-based R&D initiatives.
  • Strategic thinker with the ability to translate clinical knowledge into business growth and impact.
  • Strong leadership and team-building skills with the ability to inspire and guide a diverse team of medtech professionals.
  • Strong professional relationships with key opinion leaders practicing in key clinical areas including cancers, metabolic diseases, infectious diseases, mental health and population health.