About the role
AI summarisedThe Scientist / Senior Scientist (Infectious Diseases) at NATi will develop mRNA immunotherapies from discovery to IND-enabling stages, focusing on vaccine R&D, assay development, and characterization of RNA modalities. This role involves designing in vitro assays, writing protocols, mentoring junior staff, and supporting tech transfer to CDMOs.
ResearchFull-time
Key Responsibilities
- Support and execute the Vaccines R&D strategy in a creative, innovative manner.
- Develop and optimise laboratory methods for characterisation of the different RNA therapeutic modalities (e.g., mRNA, circRNA, saRNA, gRNA), focusing on protein translation and stability.
- Design and conduct in vitro assays to assess vaccine-specific responses and identify and quantify cellular targets and efficacy readouts for infectious diseases.
- Stay current with immunology, vaccinology literature and emerging platforms and provide scientific expertise in the areas of cellular and humoral immune responses to vaccines.
- Independently write protocols, procedures and develop and maintain SOPs to ensure reproducibility, compliance, and readiness for IND submission, contribute to CMC documentation.
- Prepare technical reports, presentations, and documentation to support internal decision-making and external regulatory submissions. Communicate results orally or written, internally or externally.
- Train and mentor junior lab personnel.
- Collaborate with scientists across multiple functions.
- Maintain accurate records using LIMS/ELN systems to support data integrity and reproducibility.
- Support tech transfer activities to external CDMOs, including preparation of reports, training, and troubleshooting support.
Requirements
- Prior experience and proven track record in the academic or biotech laboratory settings.
- Deep translational expertise in RNA-based therapeutics.
- Experience with mRNA, circRNA, saRNA, or gRNA modalities.
- Expertise in in vitro assay development for vaccine-specific responses.
- Knowledge of cellular and humoral immune responses to vaccines.
- Ability to write protocols, SOPs, and CMC documentation.
- Experience with LIMS/ELN systems for data integrity.
- Strong communication skills for internal and external reporting.
- Experience in mentoring and training junior personnel.
- Ability to collaborate across multiple functions.
- Experience in tech transfer to CDMOs.