A*STAR

Scientist, Project GLOW (GIS)

A*STAR
ResearchSingaporeOnsitePosted 3 weeks ago

About the role

AI summarised

Join Project GLOW, a national precision medicine program in Singapore focusing on the intersection of microbiome and mental health. This population-scale study (>5,000 participants) utilizes advanced long-read metagenomics, untargeted metabolomics, and host multi-omics data to investigate the impact of gut microbes on mental well-being. The role involves developing next-generation computational methods for genome-resolved metagenomics and host-microbe interaction studies.

ResearchOnsiteGenome Institute of Singapore

Key Responsibilities

  • Contribute to a population-scale study leveraging long-read metagenomics (PacBio HiFi, ONT, CycloneSeq) and untargeted metabolomics.
  • Analyze host multi-omics datasets alongside deep phenotyping, particularly mental health data.
  • Develop next-generation computational methods for genome-resolved metagenomics and intra-host diversity analysis.
  • Conduct strain-level phenotypic association studies and metagenome-scale metabolic modelling.
  • Investigate host-microbe interactions within the context of mental well-being.

Requirements

  • PhD in Computational Metagenomics
  • Strong publication track record