Postdoctoral Research Scientist (Translational Bacteriology Lab)

Key Responsibilities

• Take intellectual leadership of a monoclonal antibody (mAb) research program targeting bacterial pathogens.
• Define research priorities, milestones, and experimental strategy in alignment with the broader AMR and infectious disease program.
• Identify and develop novel scientific directions within bacterial mAb discovery and translation.
• Support and contribute to antigen discovery and prioritisation strategies, informed by bacterial genomics, surface biology, and clinical relevance.
• Analyse target conservation, expression, and accessibility across diverse bacterial isolates.
• Work closely with collaborators and existing datasets to assess translational relevance.
• Design and conduct experiments for monoclonal antibody generation, screening, and characterisation.
• Perform and interpret binding and functional assays (e.g. bactericidal, neutralisation, or opsonophagocytic assays).
• Contribute to optimisation and selection of promising antibody candidates.
• Contribute to in vitro and in vivo evaluation of antibody candidates, in collaboration with internal and external partners.
• Integrate experimental findings with genomic, phenotypic, and clinical data.
• Maintain high standards of data quality, reproducibility, and documentation.