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Illumina

Senior HPC Engineer (High Performance Computing)

Illumina
BiotechSingapore - Woodlands - NorthTechFull-time1 months ago
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About the role

AI summarised

Senior HPC Engineer responsible for ensuring Linux-based computers in Illumina sequencing platforms meet functionality, security, and robustness requirements. Role involves deep understanding of modern HPC architecture, performance optimization, benchmarking, and collaboration with cross-functional teams in Singapore and the US to support new product introduction and on-market activities.

BiotechFull-timeGeneral

Key Responsibilities

  • Engage early with the development team to understand HPC system level design and interactions with different functional components such as EE, Software/Firmware, Operating System, FPGA
  • Diagnose HPC low-level performance bottlenecks across CPU, RAM, storage, networking and peripheral drivers.
  • Collaborate with software, hardware, and systems engineering teams to qualify new software, hardware and operating workflow for the HPC.
  • Evaluate hardware components including CPUs, memory, storage, networking, and peripheral devices for platform continuity and develop sustainable solutions
  • Established work instruction of HPC integration workflow, test procedure and diagnostic workflows for engineering and manufacturing use.
  • Conduct comprehensive root-cause investigations for complex production issues using structured problem-solving methodologies (FMEA, DOE, and statistical analysis).
  • Complete Non-conformance Records based on investigation outcomes and drive the release of instruments back into production.
  • Plan and execute engineering studies to support experiments and data collection efforts.
  • Participate in continuous improvement initiatives and operational excellence programs.
  • Write and update work instructions as needed to improve test procedures.

Requirements

  • Typically requires a minimum of 5 years of related experience with a Bachelor's degree in Computing; or 3 years and a Master's degree; or a PhD without experience; or equivalent work experience.
  • Experience in Linux High Performance Computing systems (RHEL/Oracle/CentOS) in enterprise environments
  • Experience in analysing HPC workload and scheduling system eg. Slurm, RunAI, Profiling etc.
  • Experience in troubleshooting low-level performance bottlenecks across compute, storage, and networking layers
  • Deep understanding of compute system tuning for memory, CPU, and network performance
  • Good understanding of CPU architecture across Intel, AMD, and ARM with multi-threading operating system.
  • Knowledge of TCP, UDP, RDMA, and server/network interface.
  • Knowledge of modern memory technologies such as DDR4/DDR5, DIMM, LPDDR
  • Experience with scripting languages, such as Python, Perl, or Bash to extract debug information from embedded systems and high-performing compute system
  • Excellent team player, interpersonal and communication skills.
  • Willing to travel to US for extended periods to learn the technology and collaborate with US design teams.
  • Solid working knowledge of GDP, ISO & cGMP practices.
  • Experience with FDA regulated medical device product development is preferred.
  • Experience in life science–related projects or internships is advantageous; exposure to medical device environments is preferred.