A*STAR

Scientist - Cancer Genome Reconstruction (GIS)

A*STAR
ResearchSingaporeOnsitePosted 3 weeks ago

About the role

AI summarised

Join the Genome Institute of Singapore (GIS) in the Laboratory of AI in Genomics to work on the challenging problem of assembling human cancer genomes. This role applies advanced bioinformatics and deep learning approaches to reconstruct cancer genomes by leveraging routine reconstructions of normal tissue genomes.

ResearchOnsiteGenome Institute of Singapore

Key Responsibilities

  • Develop overlap between read sequences from both cancer and normal genomes.
  • Simplify cancer genome graphs while preserving both normal genome haplotypes and subclonal haplotypes within the graph.

Requirements

  • PhD in Computer Science, Applied Mathematics, or a related field.
  • Proven experience with algorithms applied to genome sequences and graphs.
  • Strong programming proficiency in C/C++, Rust, and Python.
  • Solid software engineering skills.
  • Publication record in top-tier journals or bioinformatics conferences (e.g., Recomb, ISMB, EECB, Genome Informatics).
  • Structured, independent, proactive, and collaborative working style.