About the role

AI summarised

The Staff Systems Engineer ensures system-level integrity of genetic sequencing instruments by diagnosing and resolving complex issues across hardware, software, and fluidics. The role supports New Product Introduction and on-market activities, collaborating with development teams in Singapore and the US. It involves hands-on failure analysis, root cause investigation, and continuous improvement in an ISO-certified environment.

BiotechFull-timeGeneral

Key Responsibilities

Lead and drive Instrument Operations procedures for the integration and execution of DNA Sequencing runs or Micro Array Instrumentation using standard protocols in ISO-certified environments.
Lead and drive the deployment and continuous improvement of test processes and strategies to ensure system level requirements are met, including managing test specification changes throughout the product lifecycle.
Represent Instrument Operations and engage early with development teams to understand system level design and interactions across optics, fluidics, motion system, and advanced image sensors/cameras for cutting-edge genetic analysis instruments.
Lead and coach system-level debugging and drive root cause analysis for hardware, firmware, software, and chemistry/reagent related issues on complex systems (e.g. Instruments with optical & fluidics sub-systems) and provides technical recommendations.
Diagnose system level issues and develop hypotheses based on observed failures.
Perform and coach structured root-cause analysis for complex production issues using systematic problem-solving methodologies (FMEA, DOE, and statistical analysis).
Complete Non-conformance Records based on investigation outcomes and drive release of instruments back into production.
Establish engineering studies to support various experiments and data collection efforts.
Participate in continuous improvement initiatives and operational excellence programs.
Write and update work instructions as needed to improve test procedures.

Requirements

Typically requires a minimum of 8 years of related experience with a Bachelor's Degree; or 6 years and a Master's Degree; or a PhD with 3 years' experience; or equivalent experience
Strong analytical foundation with solid understanding of statistical analysis and critical thinking skill, supported by experience using data analytics to drive decision making.
Experience in explaining and presenting complex technical issues to audiences with different backgrounds and provide sound technical recommendation and direction.
Experience developing scripts to extract/debug information from embedded systems and high-performing compute system running Oracle Linux.
Proficient in statistical analysis tools (i.e: JMP) for test data analysis, and requirement/test management tools (i.e: JAMA).
Experienced in specification characterization and driving system performance robustness.
Excellent team player, interpersonal and communication skills.
Willing to travel to US for extended periods to learn the technology and collaborate with the US design teams.
Strong working knowledge of GDP, ISO & cGMP practices.
Experience with FDA regulated medical device product development preferred.
Experience in life science–related projects or internships is advantageous; exposure to medical device environments is preferred. Familiarity with DNA sequencing, microarray platforms, liquid handling robotics, and system-level testing (hardware, firmware, software, and chemistry/reagents) is highly desirable.
Experience with Linux system will be a plus.