A*STAR

Clinical Lead, Partnership

A*STAR
ResearchSingaporeOnsitePosted 3 weeks ago

About the role

AI summarised

The Clinical Lead plays a pivotal role in guiding the clinical strategy and direction for diagnostic product development programs driven by multi-stakeholder partnerships. This role bridges clinical insight with product innovation, ensuring that diagnostic solutions emerging from collaborative programs are clinically relevant, evidence-based, and aligned with global regulatory and guideline requirements.

ResearchOnsiteDiagnostics Development Hub

Key Responsibilities

  • Lead clinical input and strategy across partnered diagnostic development programs, from early concept to validation and implementation.
  • Lead scoping and identification of companion diagnostics partnership opportunities with biotech and pharma companies.
  • Engage with clinical, academic, and industry partners to translate unmet clinical needs into Target Product Profiles (TPPs) and clinical performance specifications.
  • Review and integrate relevant clinical guidelines to define use cases and clinical utility frameworks.
  • Advise on clinical study design, endpoints, and patient selection criteria to support product development and regulatory submissions.
  • Coach and mentor internal teams (partnership, tech, QA/RA) to align clinical strategy with product requirements and partnership goals.
  • Contribute to regulatory and ethics submissions related to diagnostic validation and clinical performance studies.
  • Represent the organization in external meetings, working groups, and consortium activities.

Requirements

  • PhD in Clinical Sciences, Medicine, or related biomedical field OR Medical Degree (MD/MBBS) from a recognized university.
  • Minimum 10 years’ experience in a clinical leadership role within diagnostics or pharmaceutical development.
  • Demonstrated ability to translate clinical insights into actionable product development specifications.
  • Deep understanding of diagnostic development lifecycles, including analytical/clinical performance evaluation and evidence generation.
  • Practical knowledge of international clinical and regulatory frameworks (e.g., HSA, FDA, IVDR, NMPA).
  • Excellent communication and stakeholder management skills with experience engaging clinicians, researchers, regulators, and industry partners.
  • Experience leading clinical programs in genomics, molecular diagnostics, or infectious disease testing.